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/. does CDK5
For my read, the story is less that MIT CURES PHEAR! and more that, heh – slashdot picked up a kinase related press release – then proceeded to mangle it. Nobody tell Derek. In our study, we employ...
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Nerviano ‘n CDK
>> Update >> its really PHA-848125 WO/2007/90794 is a CDK inhibitor in combination with yada yada… from Nerviano. The single compound claimed is pictured and potentially the phase one...
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Astex: An Oral Candidate for CDK2
Astex’s fragment based discovery effort yielded an oral candidate back in ’05, and now with WO/2007/129066 & WO/2007/129062 the world can have a look. It’s probably AT-9311 even though I could’a...
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Postcards from Vienna…
Hey look what I got: Yah, its the disclosure of the discovery of PHA-848125. Not only that, its a pretty good poster. This also means I was wrong again! Posted in CDK, Nerviano
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SCH-727965
Schering-Plough’s CDK1,2,5,9 inhibitor in Ph2 for lung cancer: WO/2009/038701 has quite a bit to say about the clinical protocol including human PK and a very clean dose response measuring BrdU...
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